This is my face around the 12 the hour after applying Mirvaso. I began using the gel 4 days ago. Day 1-4 were similar. I have had some significant break through flushing while using the Mirvaso. On the 4 the day no break through. I am on no other meds. The Mirvaso is very expensive and likely cost prohibitive to most. Without insurance the cost was $200(+'-) my dermo gave me a vendor coupon to pay no more than $50 until the end of the year.