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Pinker
Joined: 23 Apr 2006
Posts: 503
Location: England
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 Posted: Thu Mar 27, 2008 8:44 pm Post subject: Glycopyrrolate cream is available in UK |
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Some of you might have seen some old articles about glycopyrrolate cream being used for facial sweating, or to be rubbed in the hands etc.. I had read about one person having this made up by a derm.. but I heard nothing else from it. Well now I know it is available in the UK.
I exchanged some emails with a rep from Nova Laboratories, from whom you might remember you can get glycopyrrolate solution from for iontophoresis, and here's what they said (the first question I asked them about the availability of glycopyrrolate in oral form).
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Dear Richard
Nova doesn’t, I’m afraid, make a tablet form of glycopyrrolate and I am not aware of anyone in the UK who does. We do, however, make oral solutions in a variety of strengths. These like the topical solution you are currently using are unlicensed products available only on prescription which are made in small quantities when requested by a doctor. The oral solution and topical solution have different uses and your GP would need to decide whether the use of the oral solution was appropriate.
I hope this helps.
Andrew
Dr Andrew Twitchell MRPharmS
Compounding Manager
Nova Laboratories Limited
Martin House, Gloucester Crescent, Wigston
Leicester LE18 4YL
Tel: 0116 2643783 or 0116 2230100 ext. 3783 |
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Dear Richard
I’m not sure exactly what the oral solution is used for but I suspect it is not for hyperhydrosis.
We do make glycopyrrolate creams. These are made to order and can be prepared in a variety of strengths and in a variety of cream bases. Your doctor is welcome to contact either me or my colleague Janet Goodall (0116 2230101) is any further information is required.
Regards
Andrew
Tel: 0116 2643783 or 0116 2230100 ext. 3783
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idripswet
Joined: 29 Nov 2005
Posts: 226
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| Posted: Fri Mar 28, 2008 9:44 pm Post subject: |
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| be nice if they made that in the U.S. |
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Pinker
Joined: 23 Apr 2006
Posts: 503
Location: England
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| Posted: Fri Mar 28, 2008 11:52 pm Post subject: |
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Someone posted on the SPW forum a while back saying they get the solution in the US, so it could be possible.
I'm gonna try this out asap |
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idripswet
Joined: 29 Nov 2005
Posts: 226
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| Posted: Mon Mar 31, 2008 11:39 pm Post subject: |
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| hmmm...if you come across that post at SPW, please post or PM me the link...thanks! |
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Pinker
Joined: 23 Apr 2006
Posts: 503
Location: England
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| Posted: Fri Apr 11, 2008 4:55 pm Post subject: |
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My doctor has ordered the 0.5% cream.. should recieve it some time next week.
The available strengths are 0.5% to 3.0%.
0.5% is 10 times stronger than the 0.05% glycopyrrolate solution I have from them so I have high hopes for this cream.. |
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Pinker
Joined: 23 Apr 2006
Posts: 503
Location: England
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| Posted: Tue Apr 15, 2008 11:30 am Post subject: |
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I recieved it this morning. One problem.. on the label it says 0.05% I thought it was 0.5% to 3.0%. Maybe they printed it wrong?
Dezza if you see your GP ask them to make it clear what the strengths are.
Last edited by Pinker on Wed Jun 18, 2008 10:09 pm; edited 3 times in total |
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Pinker
Joined: 23 Apr 2006
Posts: 503
Location: England
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| Posted: Tue Apr 15, 2008 1:12 pm Post subject: |
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Got a reply..
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We have made creams ranging in strength from 0.01% to 10% with the most usual range being between 0.05 and 3%. If the 0.05% product is not effective your GP will probably increase the strength to find the lowest effective strength.
Regards
Andrew
Dr Andrew Twitchell MRPharmS
Compounding Manager
Nova Laboratories Limited
Martin House, Gloucester Crescent, Wigston
Leicester LE18 4YL
Tel: 0116 2643783 or 0116 2230100 ext. 3783
Fax: 0116 2230101
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Pinker
Joined: 23 Apr 2006
Posts: 503
Location: England
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| Posted: Wed Apr 16, 2008 2:45 pm Post subject: |
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Day 1: not really any noticable change anywhere
I've made an appointment to go back and change the dose to like 3% or something. 0.05% is too low IMO. |
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Pinker
Joined: 23 Apr 2006
Posts: 503
Location: England
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| Posted: Sat Apr 19, 2008 5:19 pm Post subject: |
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Day 3... The cream seems to be taking some effect on the sides of my feet, but not on my fingertips. I did an iontophoresis treatment yesterday so they do feel a little bit dryer at the moment.
I've got another GP appointment for next week. As someone said on the SFW forum if you read the case studies and reports on glycopyrrolate cream the patients are treated with 1% strength.. compared to the 0.05% cream i'm using this is 20 times stronger!
http://www.socialphobiaworld.com/postx16795-0-10.html |
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dezza
Joined: 13 Aug 2007
Posts: 32
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| Posted: Tue Apr 22, 2008 3:00 pm Post subject: |
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Hi Pinker,
Just thought I'd update on this, I saw my GP today and she prescribed the 1% solution - the cream wasn't on the computer system though, so it may take a couple of days longer for the pharmacy to get this in.
I tried a few pharmacies in the local area, and quite a few don't have an account or any contact with Nova, so they were unable to help. I have left it with one which say they'll call me tomorrow to say if they can or can't get it in.
How are you getting yours? Are you using a big pharmacy such as Boots? If so, how long's it taking them to get it in?
Dezza |
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Pinker
Joined: 23 Apr 2006
Posts: 503
Location: England
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| Posted: Tue Apr 22, 2008 9:21 pm Post subject: |
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What strength solution did you use before? I used 0.05% so 1% must be really strong.
I get my prescriptions at the small chemist next door to the doctors.. i think its cohens. It only takes a few days. My doctors arranged with Andrew over the phone to get it on special prescription because theres no licence for glycopyrrolate in the uk.
I might ask for the solution again in a stronger strength.. but im not sure. ideally i dont want to use the solution but i'll be putting my hope in the cream. |
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dezza
Joined: 13 Aug 2007
Posts: 32
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| Posted: Wed Apr 23, 2008 5:39 am Post subject: |
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I've been prescribed the 1% strength cream, which I assumed would be one level up from 0.5%.
My GP was due to call Nova yesterday afternoon and get back to me if there was a problem, so now I'd assume everything is OK.
Do you know if it comes with directions on how to use? If so, do you know when it is applied and how often - is it like using Driclor, where it's applied at night and washed off next morning? |
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Pinker
Joined: 23 Apr 2006
Posts: 503
Location: England
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| Posted: Wed Apr 23, 2008 12:12 pm Post subject: |
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Oh right I thought you had been prescribed the 1% solution (liquid), not the cream. I was going to say iontophoresing the liquid is a hell of a lot stronger!
Looking forward to how you get on. Im seeing the GP on friday.. I think 1% or more is necessary for the hands and feet. It doesnt come with directions, but I apply it at night as I would a roll on. |
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dezza
Joined: 13 Aug 2007
Posts: 32
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| Posted: Wed Apr 23, 2008 3:09 pm Post subject: |
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I don't think I'd be in any rush to try the 1% liquid, seeing that it starts at 0.05%!
I'll post on here if it works or not - fingers crossed - would be interesting to hear how you get on with a stronger concentration. |
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dezza
Joined: 13 Aug 2007
Posts: 32
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| Posted: Fri Apr 25, 2008 10:04 am Post subject: |
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I've just picked up the cream, going to use it within the next couple of days.
I will try putting it on at night and washing it off in the morning - although may it be best to leave it on for say half an hour? If it's the same sort of strength as used in iontophoresis, is it safe to leave it on all night? |
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